Indications and Dosage
Oral
Excessive mucus or sputum
Adult: Initially, 2,250 mg daily in divided doses, reduce to 1,500 mg daily when satisfactory response is obtained.
Child: 2-5 years 62.5-125 mg 4 times daily; 6-12 years 250 mg tid. |
Administration
Should be taken with food.
|
Contraindications
Active peptic ulceration. Children <2 years.
|
Special Precautions
Patient with history of gastroduodenal ulcers, bronchospasm, asthma or respiratory failure. Debilitated patients. Children ≥2 years. Pregnancy and lactation.
|
Adverse Reactions
Significant: Gastrointestinal bleeding. Rarely, urticaria and bronchospasm.
Immune system disorders: Anaphylactic reactions, fixed drug eruption. Gastrointestinal disorders: Nausea, vomiting, diarrhoea, gastric discomfort. Respiratory, thoracic and mediastinal disorders: Bronchorrhea. Skin and subcutaneous tissue disorders: Rashes. Rarely, bullous dermatitis (e.g. Stevens-Johnson syndrome, erythema multiforme). |
Overdosage
Symptoms: Gastrointestinal disturbance (e.g. gastralgias, nausea, vomiting). Management: May perform gastric lavage, followed by observation.
|